Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 07946A | 07946A | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, L210W, T215Y | V75I, N348I | K103N | V108I | V35I, V60I, K122P, D123E, I132L, Q174R, D177E, I178L, G196E, Q197K, T200A, H208Y, R211K, V245VI, A272P, K277R, P313PS, L325I, Q334L, G335N, I341F, R356RK, G359GS, T386I, K388KR, A400T |
| >07946A| codons 1-400 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKVIDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DPEFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPELVI YQYMDDLYVGSDLEIEKHRAKIEELRQYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIILPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAE LELAENREILKESVHGVYYDPSKDIIAEIQKQGLNQWTYQFYQEPFKILKTGKYAKMRSA HTNDVKQLTEAVQKIATESIVIWGKIPRFKLPIQKETWET |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50V, I54V, L76V | L10F | T4S, L63P, H69Q, A71V, L89I |
| >07946A| codons 1-99 PQISLWQRPFVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGVGGFVKVRQYD QIPIEICGQKVIGTVVVGPTPVNIIGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |