<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54M, L76V, I84V, L90M L33I, G73S, L89V L10I, V11L, I13V, Q18H, K20V, M36IL, I62V, L63P, A71IV  
>07893A| codons 1-99
PQITLWQRPILTVKIGGHLVEALLDTGADDTVIEELNLPGRWKPKMIGGIGGFMKVRQYD
QVPIEICGHKVISTVVVGPTPVNVIGRNVMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219N Y181V, Y188L V179VD V35VI, K43KR, E44D, A98S, K101Q, K103KR, L109I, V118I, K122E, D123E, I135V, S162SN, K173KR, V189I, I202IV, H208Y, D218E, A272S, L283I, T286A, I293V, R356RK, R358K, G359S, A371V, I375IV, K390R  
>07893A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELERDGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLQKRKSVTVIDVGDAYFSIPL
DEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRRQNPDIDI
VQYVDDLLIGSDLEIGQHRTKVEELRQYLWRWGFYTPENKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLIRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMKSA
HTNDVKQLTEVVQKVATESIVIWGKTPKFRLPIQKETWEA

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010