<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54L, V82A, L90M L33F, K43T L10I, I13V, K20KT, D60E, Q61E, I62V, L63P, I66V, V75VI, V77I, I93L, C95F  
>07841A| codons 1-99
PQITLWQRPIVTVKIGGQLTEALLDTGADDTVFEEMNLPGRWTPKIIGGIGGFLKVRQYE
EVPIEVCGHKAIGTILIGPTPANIIGRNLMTQLGFTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y   K101E, Y181C, G190A A98G, F227L E6K, M16V, K20KR, V35L, T39K, K43E, E44D, D86DN, W88C, V118I, K122E, S162Y, R172RK, K173KE, E203K, L205F, Q207E, H208Y, R211K, H221CY, K223E, A272P, T286A, I293V, G333D, Q334H, R358K, G359S, T386TI, K390R  
>07841A| codons 1-399
PISPIKTVPVKLKPGVDGPRVKQWPLTEEKIKALLEICKELEEDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQNFCEVQLGIPHPGGLEKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFKEQNPDIVI
CQYMDDLYVASDLEIGQHRTKIKEFREYLWKWGFYTPDKKYQEEPPLLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQDHGQWTYQIYQEPFKNLKTGKYARMKSA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010