<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y V75M K103N V108I, K238T P4S, V35I, K43Q, E44D, E53ED, V90VI, K101Q, V118I, K122E, D177E, I178L, V189I, Q207K, H208Y, R211D, H221HY, E224D, L228LH, V245E, K277R, I293V, E297K, I329V, Q334L, M357T, A371V  
>07783A| codons 1-399
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEQDGKISKIGPDNPYNTPV
FAIKKKNSTKWRKLMDFRELNKRTQDFWEIQLGIPHPAGLQKNKSVTILDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPELVI
YQYMDDLYIGSDLEIGQHRTKIEELRKYLWDWGFYTPDKKYQKDPPFHWMGYELHPDTWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGLGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEVVQKIATESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82C, L90M G73S L10I, K20I, M36I, I62IV, L63P, I66F, C67CY, A71V, I93L  
>07783A| codons 1-99
PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYD
QVPIEFYGHKVISTVLVGPTPCNIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010