<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Y115F   V106M, Y181C V179D T39A, W88S, K173E, Q174K, E204Q, Q207E, R211K, F214L, A272P, T286P, V292I, I293V, E297A, K311R, I326V, G333GE, Q334L, M357T, K385R, K390R, Q394N  
>07714A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPV
FAIKRKDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAGLKKKKSMTVLDVGDAFFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFREKNPDIDI
CQYMDDLYVGSDLEIGQHRTKIEQLREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGPKALTEIVPLTAEAE
LELAENREILREPVHGVYYDPSKDLVAEIQKQELGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEAVQKIATESIVIWGRTPKFRLPINKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16A, E35D, N37D, I62V, L63P, V77I, I93L  
>07714A| codons 1-99
PQITLWQRPLVTIKIAGQLKEALLDTGADDTVLEDMDLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010