<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115F, M184V A62V, V75T, T215D L100I, K103N   V118I, K122KE, D123EK, I135T, T200AE, I202V, K238KR, V245M, A272P, I293V, D324DE, I329L, Q334E, R356K, A376S, T386V, E399D  
>07649A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FVIKKKDSTKWRKVTDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAFFSIPL
DEKFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHREKVEELRQHLLRWGFDTPDKKHQKEPPFLWMGYELHPDRWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAELQKQGEGQWTYQIYQEPFKNLKTGKYAKMRGA
HTNDVKQLTEAVQKISTESIVIWGKVPKFKLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M Q58E, G73S L10V, E35D, M36I, N37T, I62V, L63P, A71V, I72V, V77I  
>07649A| codons 1-99
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEDITLPGRWKPKMIGGIGGFIKVREYD
QVPIEICGHKVVSTVLIGPTPVNIIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010