Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54V, V82A, L90M | L33LF, G73S | L10I, N37NCSY, I62V, L63P, H69K, A71IV, V77I, I93IM |
| >07445A| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVFEEMYLPGRWKPKIIGGIGGFVKVRQYD QVPIEICGKKVISTVLIGPTPANIIGRNLMTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | Y181C | K20KR, T69N, K122E, I135M, Q174N, V245M, A272P, K277R, T286A, E297Q, Q334E, R356K, M357T, I375IV, A376S, T386I, K390R |
| >07445A| codons 1-399 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKNNPDIVI CQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTQEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYAKTRGA HTNDVKQLTEAVQKVSTESIVIWGKIPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |