Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70R, L74V, T215F | K219W, N348I | Y181V, G190E | K11KR, V35VI, T39TA, K101T, V118VI, K122E, E138A, S162CY, R172RK, H208HY, L210LS, L228H, V245MR, R284K, A288S, I293V, E298A, E312A, I326V, Q334E, M357T, V365VI, A376T, T386A, K390KR |
| >07444A| codons 1-400 PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALIEICAELEKEGKISKIGPENPYNTPV FAIKKKNSDRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLTKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFKKQNPDIVI VQYMDDLYVESDLEIGQHRTKIEELRQYLSRWGFFTPDWKHQKEPPFHWMGYELHPDKWT VQPIRLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGTKSLTEVVPLTEAAE LELAENREILKAPVHGVYYDPSKDLVAEIQKQGEGQWTYQIYQEPFKILKTGKYARTRGA HTNDIKQLTEAVQKITTESIVIWGKAPKFRLPIQKETWEA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, L90M | L10I, K55R, I62V, L63P, A71T, I93L, C95F |
| >07444A| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFVRVRQYD QVPIEICGHKTIGTVLVGPTPANIIGRNLMTQLGFTLNF |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |