<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Q151M, M184V F116Y K103N V108I V35VI, V60I, S68G, T69N, K122E, I135T, S162A, I167V, R211K, V245EK, A272P, K277R, T286N, L301I, D324E, K350R, M357V, T386TI, K390R  
>07393A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDGNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYYSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQASMTKVLEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGNKALTEVIPLTEEAE
IELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLRTGKYARVRGA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84V, L90M L10F I13IV, K14KR, L63P, A71I, I72S, I93L  
>07393A| codons 1-99
PQITLWQRPFVTVRIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIPIEICGHKISGTVLVGPTPVNVIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010