<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   T12S, I13V, I15V, L19I, K20T, M36I, N37ND, R41K, L63P, H69K, V82I, L89M, I93L  
>07344A| codons 1-99
PQITLWQRPLVSVKVGGQITEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPINIIGRNMMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T215Y   K103N, Y181C V108I, E138EAKT K20R, V35T, T39E, K43R, E44ED, K122P, D123N, I135IT, K173R, D177E, I178L, V179VI, V189VI, T200S, Q207E, L228R, V245K, A272P, K277R, T286A, A288T, E291D, V292I, I293V, P294T, S322SA, K323KR, D324E, Q334H, G335D, R356K, M357R, G359A, T377L, I382V, K390R  
>07344A| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEELERDGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DPNFRKYTAFTIPSTNNTTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRQNPELII
CQYMDDLYIGSDLEIGQHRSKIEELREHLLRWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKTLTDIVTLTEEAE
LELAENREILKEPVHGVYYDPARELIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRRAA
HTNDVKQLTEAVQKIALESIVVWGKTPKFRLPIQKETWEA

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010