<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, V75M, M184V, L210W, T215Y K219Q K103NS Y318F E28EKQ, T39E, E44ED, V60I, A98AS, K101KQ, V118I, K122E, D123E, I135T, S162SDGN, Q174K, N175Y, D177DN, G196E, Q197QE, R211K, D218E, L228H, Q242H, A272P, L283LI, P345L, G359S, A371V, S379C, K390R  
>07342A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTQEKIKALVEICEELEKDGKISKIGPENPYNTPI
FAIKKKNSDRWRKLMDFRELNKRTQDFWEVQLGIPHPSGLQKSKSVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKKYPNIVI
YQYVDDLYVGSDLEIEEHRTKIEELRQHLWKWGFYTPEQKHQKEPPFHWMGYELHPDKWT
VHPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVFYDPSKDLIAEIQKQGQGQWTYQIYQELFKNLKTGKYARMRSA
HTNDVKQLTEVVQKIATECIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I50IV, I54AV, V82ST, L90LM   L10V, E34EQ, Q61D, L63P, A71V, I72IV, T74S, V77I, I93L  
>07342A| codons 1-99
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLQEMNLPGRWKPKMIVGVGGFVKVRQYD
DIPIEICGHKVVGSVLIGPTPTNIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010