<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210LW, T215Y   Y181C, G190A K101HQ V35M, K43E, E44D, V118I, D121Y, K122E, I135T, S162CY, D177E, G196GE, Q197EK, T200E, E203K, H208HY, R211KT, K223E, Q278H, T286A, M357MT, R358K, V365VI, I375IV, A376S, T386I, K390R, E399ED K13R
>07315A| codons 1-400
PISPIETVPVKLRPGMDGPKVKQWPLTEEKIKALMEICTELEEDGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSIPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPEIVI
CQYVDDLYVASDLEIEKHREKIKELRQYLWTWGFYTPDKKHQEEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGAKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTKGA
HTNDIKQLTEAVQKVSTESIVIWGKIPKFRLPIQKETWDA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, V82A, I84V, L90M L33F, F53L, Q58QE L10I, K20R, E35D, M36I, N37D, D60DE, I62V, L63P, A71V  
>07315A| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVFEDIDLPGRWKPKIIGGIGGLIKVREYE
QVPIEICGHKVIGTVLVGPTPANVIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010