<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A, I84V   L10I, I15V, K20R, M36I, N37D, K43S, I62V, L63C, A71V, I72T, T74A, I93L  
>07314A| codons 1-99
PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEEIDLPGRWSPKIIGGIGGFVKVRQYD
QVCIEICGHKVTGAVVVGPTPANVIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, Q151M, M184V, T215F K219Q Y181C, G190A K101H, V108I V21I, T27S, K49Q, A98S, D123E, Q174R, D177E, I178L, G196E, F214L, D218E, K249R, A272P, K275R, K277R, Q278H, I293V, E297K, Q334E, M357S, A360T, K390R, K395R, E399D  
>07314A| codons 1-399
PISPIETVPVKLKPGMDGPKIKQWPLSEEKIKALVEICTEMEKEGKISQIGPENPYNTPV
FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLHKKKSVTILDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKRNPELVI
CQYVDDLYVASDLEIEQHRTKIEELRQHLLRWGLFTPEQKHQKEPPFLWMGYELHPDKWT
VQPIVLPERDSWTVNDIQKLVGKLNWASQIYPGIRVRHLCKLLRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYARSRGT
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQRETWD

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010