<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A L24I, Q58QE L10I, L19LQ, N37D, I62V, L63P, I64IV, H69Q, T74TS, V77I  
>07290A| codons 1-99
PQITLWQRPIVTIKIGGQQKEALIDTGADDTVLEEMDLPGRWKPKIIGGIGGFVKVREYD
QVPVEICGQKAIGSVLIGPTPANIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210LW, T215Y       K20R, V35M, E44ED, R83RK, I135IT, G196E, T200TI, I202V, S251SI, A272P, I293V, E297R, Y339F, A360V, T386IV, K390R, E399D  
>07290A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTELEKDGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIEQHRIKVEELRQHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDIWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTFQIYQEPFKNLKTGKYARMRGV
HTNDVKQLTEAVQKIATESIVIWGKVPKFRLPIQKETWD

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010