<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T215Y N348I K101P, K103N   V21I, V118I, E138A, I142T, S162C, V179I, L210F, P243S, A272P, K277R, T286A, E297R, G333E, Q334H, G335C, M357T, K388KR, E399D  
>07289A| codons 1-399
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLPKNKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSINNATPGTRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIII
YQYMDDLYVGSDLEIGQHRTKIEELRQHLFRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQSIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQEHCQWTYQIYQEPFKILKTGKYARTRGA
HTNDVKQLTEAVQKIATESIVIWGKTPRFKLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54M, L90M L33F L10I, E34D, M36L, N37S, K45R, R57K, I62V, L63P, I64L, A71I  
>07289A| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVFDELSLPGRWKPRMIGGIGGFMKVKQYD
QVPLEICGHKIIGTVLVGPTPVNIIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010