<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74I, M184V, T215F K219Q, N348I K101E, Y181C, G190A   K20R, V35L, V90I, I94L, K122E, D123N, T200A, E203Q, Q207D, H208Y, R211K, L228H, V245K, A272S, I293V, E297A, I329L, Q334E, I341F, A376S, T386I, K390R, E399D  
>07242A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICTELEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKIVDFRELNKRTQDFWEIQLGLPHPAGLEKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYVDDLYVASDLEIGQHRAKIQELRDYLLKWGFFTPDQKHQKEPPFHWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKALTEVVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGEGQWTYQFYQEPFKILKTGKYARMRGA
HTNDVKQLTEAVQKISTESIVIWGKIPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54A, V82S, L90M L33F L10I, K20R, E34N, E35D, M36I, N37E, K55R, I62V, L63P, C67D, A71V, T74S, V77I, Q92K, I93L  
>07242A| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVFNDIELPGRWKPKIIGGIGGFARVRQYD
QVPIEIDGHKVIGSVLIGPTPSNIIGRNLMTKLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010