Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54A, V82S, L90M | L33F | L10I, K20R, E34N, E35D, M36I, N37E, K55R, I62V, L63P, C67D, A71V, T74S, V77I, Q92K, I93L |
| >07242A| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVFNDIELPGRWKPKIIGGIGGFARVRQYD QVPIEIDGHKVIGSVLIGPTPSNIIGRNLMTKLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V, T215F | K219Q, N348I | K101E, Y181C, G190A | K20R, V35L, V90I, I94L, K122E, D123N, T200A, E203Q, Q207D, H208Y, R211K, L228H, V245K, A272S, I293V, E297A, I329L, Q334E, I341F, A376S, T386I, K390R, E399D |
| >07242A| codons 1-399 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKIVDFRELNKRTQDFWEIQLGLPHPAGLEKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYVDDLYVASDLEIGQHRAKIQELRDYLLKWGFFTPDQKHQKEPPFHWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKALTEVVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGEGQWTYQFYQEPFKILKTGKYARMRGA HTNDVKQLTEAVQKISTESIVIWGKIPKFRLPIQKETWD |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |