<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, M184V, L210W, T215Y   K103N Y318F V35T, T39A, K43Q, S68G, A98S, D121C, K122E, I135T, S162A, D177E, T200A, R211RK, L228Q, A272P, K277R, T286A, E297Q, I329V, Q334QR, G335GD, R356RK, G359S, A371V  
>07155A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEQEGKISKIGPENPYNTPV
FAIKKKDGTKWRKIVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
CEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRQHLWKWGFYTPDKKHQKEPPFQWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTQEAE
LELAENREILKEPVHGVFYDPSKDLIAEVQKQGRDQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEVVQKIATESIVIWGKTPKFKLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54M, V82A L10F, L33F L63P, I64L, A71V, I72V, I93L  
>07155A| codons 1-99
PQITLWQRPFVTIKIGGQLKEALLDTGADDTIFEEMNLPGRWKPKIVGGIGGFMKVRQYD
QIPLEICGHKVVGTVLVGPTPANIIGRNLLTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010