<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47IV, I54A, V82F L33F, L89V L10I, I13V, Q18QH, N37H, D60E, Q61DEKN, I62IV, L63P, I66F, A71T, I72V, V77I, I93IV P39E
>06983A| codons 1-99
PQITLWQRPIVTVKIGGHLKEALLDTGADDTVFEEMHLEGRWKPKIVGGIGGFAKVRQYE
NVPIEFCGHKTVGTVLIGPTPFNIIGRNVLTQVGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215Y       V35M, T39TA, K43N, A98S, V118I, K122KE, K173Q, I178IM, T200K, Q207E, L210LFS, K223KQ, L228LR, V245E, A272P, T286A, A288T, V292VI, I293V, D324DE, I329V, Q334QL, M357T, A371AV  
>06983A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAELENEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRQQNPDMVI
YQYVDDLYVGSDLEIGQHRKKIEELREHLSRWGFYTPDKKHQQEPPFRWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKTLTEIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEVQKQGLGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEVVQKIATESIVIWGKTPKFKLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010