Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50V, I54V, V82ACGS, L90M | L33F | L10I, I13V, N37H, R41K, I62V, L63S, I64IM, A71V, V77I, Q92R, I93L, C95F |
| >06982A| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVFEEMHLPGKWKPKIIGGVGGFVKVRQYD QVSMEICGHKVIGTVLIGPTPSNIIGRNLMTRLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, L210W, T215Y | K101P, K103N | V108VI | E6K, V118VI, K122E, D177E, T200A, E203D, Q207E, R211K, A272P, K277R, I293V, E297K, V317A, Q334L, R356K, A360T, V365VI |
| >06982A| codons 1-399 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLPKNKSVTILDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRAKIDELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYAKMRGT HTNDIKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWE |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |