<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A L10F, L89V V11L, I13V, L19Q, K20I, M36I, L63P, H69K, K70R, A71T, T91S  
>06981A| codons 1-99
PQITLWQRPFLTVKIGGQQIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYD
QIPIEICGKRTIGTVLVGPTPANIIGRNVLSQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V T215I, K219E K103N, G190A   V60I, K102N, V106I, K122KE, D123E, K173T, T200A, E248D, A272P, Q278H, T286A, I293V, P294AT, E297AT, Q334L, G335S, M357T, A371V, A376T, K390R, E399D  
>06981A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKNNKSITVLDVGDAYFSVPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIVI
YQYVDDLYVASDLEIGQHRAKIEELRQHLLRWGFITPDEKHQKEPPFLWMGYELHPDKWT
VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTEVVTLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLSQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEVVQKITTESIVIWGKTPKFRLPIQKETWD

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010