<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54IL, I84V, L90M L10F K14R, Q18R, K20I, L63P, H69Q, A71V, Q92R, I93M  
>06908A| codons 1-99
PQITLWQRPFVTIRIGGRLIEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFLKVRQYD
QIPIEICGQKVIGTVLVGPTPVNVIGRNLMTRMGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215Y   K103N V108I L34I, T39A, K102KHNQ, V118I, K122E, I135T, T139I, S162A, D177EG, T200A, F214L, H221Y, L228H, Q242QH, K249R, A272AS, R284K, T286A, A288S, I293V, E297EQ, K311R, D324E, I326V, I329IV, M357T, S379SC  
>06908A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKAIVEICAELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTILDVGDAYFSIPL
DEDFRKYTAFTIPSTNNEIPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPGIVI
YQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGLYTPDKKYQKEPPFHWMGYELHPDKWT
VHPIVLPERDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLKGAKSLTEVVPLTQEAE
LELAENREILREPVHGVYYDPSKELVAEVQKQGQGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEAVQKIATECIVIWGKTPKFKLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010