<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y V75VA     K20R, V35L, T39TA, E44D, K49R, V106I, V118I, K122E, I135T, K166Q, E169D, P170L, Q207QE, R211RK, D218E, K223Q, K277R, Q278H, E291D, I293V, I326IV, I329IV, K350R, G359S, A371V, K390R  
>06836A| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICAELEKDGKISRIGPENPYNTPV
FAIKKKNSDKWRKLADFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTQILDLFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPEKKHQQEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGTKALTDVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEVQKQGQGQWTYQIYQEPFKNLRTGKYARMRSA
HTNDVKQLTEVVQKIATESIVIWGKTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, I84V, L90M V11I, G73S L10I, T12TKPQ, I15V, G16GA, L19P, K20I, E21ED, M36I, L63P, A71V, I85V  
>06836A| codons 1-99
PQITLWQRPIIQIKVAGQPIDALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYD
QIPIEICGHKVISTVLVGPTPTNVVGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010