<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, G48V, I54T, V82S L24I, L33F, Q58E L10I, I13V, Q61N, L63T, I64V, I72V, T74A, V77I  
>06749A| codons 1-99
PQITLWQRPIVTVKIGGQLKEALIDTGADDTVFEEMNLPGRWKPKIIVGIGGFTKVREYD
NITVEICGHKAVGAVLIGPTPSNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, V75M, L210W, T215Y   K101E, Y181I, G190S E138K E6K, K20R, V35T, E44D, K49R, V60I, V118I, K122E, D123E, I135T, S162D, D177E, V179I, G196E, E203K, Q207E, R211K, K223Q, A272P, K277R, I293V, P294Q, E297Q, Q334H, K350R, R358K, G359S, T369V, A371V, I375AV, T386I I159L
>06749A| codons 1-400
PISPIKTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTELEKDGKISRIGPENPYNTPI
FAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSTNNKTPGIRYQYNVLPQGWKGSPALFQDSMTKILEPFRKQNPEIII
IQYMDDLYVSSDLEIEQHRTKIKELREHLWKWGFYTPDKKHQQEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVQLTQEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHGQWTYQIYQEPFKNLRTGKYARMKSA
HTNDVKQLVEVVQKVATESIVIWGKIPKFKLPIQKETWEA

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010