<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, L210CW, T215Y   V106A   T39A, A98S, K101Q, V118I, D123E, I135IL, I142V, T200A, R211K, T240K, E248N, A272P, K281R, R284K, T286A, V292I, E297K, M357T, R358K, A376T, T386A, E399D  
>06722B| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLQKKKSATVLDVGDAYFSIPL
DKEFRKYTAFTIPSLNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWK
VQPIVLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLKGAKALTEIIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTKGA
HTNDVKQLTEAVQKITTESIVIWGKAPKFKLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82T, L90M   L10I, K20I, M36MI, K55R, D60E, Q61E, I62V, L63P, C67Y, H69K, A71IV, T74S  
>06722B| codons 1-99
PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFIRVRQYE
EVPIEIYGKKVIGSVLVGPTPTNIIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010