<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M L10F, G73S K14R, I15V, Q18H, K20V, E34Q, E35D, M36I, N37D, I62V, L63P, A71I, I72K, P79A, I85V, I93L  
>06691A| codons 1-99
PQITLWQRPFVTIRVGGHLVEALLDTGADDTVLQDIDLPGRWKPKIIGGIGGFVKVRQYD
QVPIEICGHKIKSTVLVGATPVNVVGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74I, M184V, L210W, T215Y K219Q K103N, Y181C, G190GA   K20R, V35I, T39TA, E44D, V118I, K122E, I135T, I178IM, T200TA, E203K, Q207DE, H208Y, R211K, D218E, L228H, V245E, K277R, Q278H, T286A, A288AT, E297K, I326V, Q334D, R356K, G359S, S379C, K390R  
>06691A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICAELEKDGKISKIGPENPYNTPV
FAIKKKNSDKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI
CQYVDDLYVASDLEIGQHRAKIKELREYLWKWGFYTPEQKHQKEPPFHWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGAKTLTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGDGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEAVQKIATECIVIWGKTPKFRLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010