<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I47V, I54IM, I84V L33F, Q58QE, L89V L10I, I13V, K14R, I15V, Q18H, K20T, M36MI, D60DN, I62V, L63H, I66L, K70E, A71T, G73D, Q92K  
>06570B| codons 1-99
PQITLWQRPIVTVRVGGHLTEALLDTGADDTIFEEINLPGRWKPKMVGGIGGFMKVREYN
QVHIELCGHETIDTVLVGPTPVNVIGRNVLTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74I, M184V, T215F K219Q K103N V108I, F227L K20R, K43Q, V60I, T69N, V90I, D121H, K122E, I135T, D177E, G196E, Q197K, I202V, E203EK, H208Y, R211K, H221Y, K223E, L228H, A272P, K275Q, V276T, L283I, I293V, E297K, D324E, Q334E, R356K, M357MV, R358K, G359A, Q373N, K390R  
>06570B| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEQEGKISKIGPENPYNTPI
FAIKKKNSNRWRKIVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
YQYVDDLYVGSDLEIEKHRTKVKELRQYLLKWGFFTPDQKYQEEPPLHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIQTKQLCKLIRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGEGQWTYQIYQEPFKNLKTGKYAKVKAA
HTNDVKQLTEAVNKIATESIVIWGKTPKFRLPIQKETWEA

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010