<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, M184V, L210W, T215Y V75A V106A, G190A F227L T39E, E44D, K102R, V118I, K122E, D123N, I135T, V179I, G196E, T200TK, I202V, E203EK, H208Y, R211K, K223Q, A288S, I293V, I329V, K350R, M357T, A371V, A376S, T386TI, K390R, E399D  
>06566A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICEELEKDGKISKIGPENPYNTPV
FAIKKKNSTKWRKIADFRELNKRTQDFWEVQLGIPHPAGLKRKKSATVLDVGDAYFSIPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII
YQYVDDLYVASDLEIEQHRKKVKELRQYLWKWGFYTPDKKHQQEPPLLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQGQWTYQIYQEPFKNLRTGKYARTRGA
HTNDVKQLTEVVQKISTESIVIWGKIPKFRLPIQKETWDA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82F, I84V, L90M F53L L10I, I13V, K20I, E35N, M36I, N37S, D60E, L63P, A71V, I93M  
>06566A| codons 1-99
PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLENISLPGRWKPKIIGGIGGLVKVRQYE
QIPIEICGHKVIGTVLVGPTPFNVIGRNLMTQMGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010