<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115F, M184V   K103N, Y181C   V35T, T39E, S48T, V60I, D121H, K122E, I135T, K173T, Q174K, D177E, I178L, T200A, Q207E, V245Q, A272P, K277R, E291D, V292I, I293V, Q334R, G335D, R356K, G359T, T369A, T377L, K390R  
>06552A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAFFSVPL
HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPELVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGRDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLAEAVQKIALESIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A   L10I, I13V, G16GE, L19I, K20R, M36I, N37ND, R41K, Q61N, L63PS, H69K, T74S, L89M, I93L  
>06552A| codons 1-99
PQITLWQRPIVTVKIEGQIREALLDTGADDTVLEEIDLPGKWKPKIIGGIGGFVKVRQYD
NISIEICGKKAIGSVVVGPTPANIIGRNMLTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010