<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76LV, V82VFI, L90M L33I, G73C, L89V L10I, V11L, I13V, K20V, M36I, P39T, I62V, L63P, I64V, T74S, I93IL  
>06500A| codons 1-99
PQITLWQRPILTVKIGGQLVEALLDTGADDTVIEEINLTGRWKPKIIGGIGGFVKVRQYD
QVPVEICGHKAICSVVVGPTPINIIGRNVMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, M184MV, L210W, T215Y   Y181YC, Y188YFHL   K43N, A98S, V118I, K122E, K166R, F171Y, T200A, Q207E, R211K, L228H, A272S, K277R, E297EK, A360T, K366KR, A400AT  
>06500A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELENEGKISKIGPENPYNTPV
FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPYRKQNPDIVI
CQYVDDLLVGSDLEIGQHRAKIEELREHLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGT
HTNDVRQLTEAVQKIATESIVIWGKTPKFKLPIQKETWET

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010