<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, V75ST, L210W, T215Y K219R   A98G, V108I V35VI, K43N, E44D, I94L, V118I, K122E, D123E, I178M, V179VI, G196E, T200TA, E203K, H208HY, R211D, K223Q, F227Y, D237E, A288S, I293V, E297K, G335S, G359S, A371V, K390R, E399ED  
>06472A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELENDGKISKIGPENPYNTPV
FAIKKKNSTKWRKITDFRELNKRTQDFWEVQLGLPHPGGLKKKKSVTILDVGDAYFSIPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMII
YQYMDDLYVGSDLEIEQHRAKIKELRQYLWDWGFYTPDRKHQQEPPYLWMGYELHPEKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQSQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEVVQKIATESIVIWGKTPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82S, L90M   L10I, L19I, K20R, E35D, M36I, N37D, I62V, L63P, A71V, T74S, V77VI, I93IM, C95L  
>06472A| codons 1-99
PQITLWQRPIVTIKIGGQIREALLDTGADDTVLEDIDLPGRWKPKMIVGIGGFVKVRQYD
QVPIEICGHKVIGSVLIGPTPSNIIGRNLMTQMGLTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010