<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, T215F K219W K101KE, Y181C, G190A   K20R, V35I, V60I, T69N, K122E, I135T, T139K, K173KR, Q174E, V179I, H208HY, L228H, A272P, I293V, E297K, V365I, A376T, E399D  
>06461A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPI
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNEKPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRENPDIII
CQYMDDLYVASDLEIGQHRTKIEELRQYLLRWGFFTPDWKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDIKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I47IV, I54V, I84V, L90M L10F, Q58QE, G73S T12K, K14M, I15V, L19P, K20V, M36I, R57K, I62V, L63P, A71V, I72IL, N83S, I85V  
>06461A| codons 1-99
PQITLWQRPFVKIMVGGQPVEALLDTGADDTVLEEINLPGRWKPKIVGGIGGFVKVKEYD
QVPIEICGHKVLSTVLVGPTPVSVVGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010