<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, L74V, M184V D67G, K219Q K103N, Y181C K238T S68G, K101R, Q174R, Q207E, R211K, D218E, T286TA, E312A, Q334L, M357KR, R358G, V365I, K390R, E399G  
>06458A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKGGTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLRKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPDIVI
CQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPEQKHQKEPPFLWMGYELHPDTWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTEEAE
LELAENREILKAPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARRGGA
HTNDIKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWGA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, I84V, L90M V11I, L33F, Q58E L10I, L19I, N37H, R41K, K55R, I62V, L63P, I64M, A71V, T91S, Q92K, I93L, C95F  
>06458A| codons 1-99
PQITLWQRPIITIKIGGQIKEALLDTGADDTVFEEMHLPGKWKPKLIGGIGGFVRVREYD
QVPMEICGHKVIGTVLVGPTPANVIGRNLMSKLGFTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010