<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T215F N348I K103N, Y181C   V35K, K104R, K122E, I135V, I142T, E169D, G196R, T200A, H208Y, R211K, K223Q, L228R, A272P, E297K, S322T, I329L, Q334E, R356K, A360T, A376T, E399D  
>06415A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNRSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSVNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI
CQYMDDLYVGSDLEIRQHRAKIEELRQYLLKWGFFTPDKKHQQEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPTKDLIAELQKQGEGQWTYQIYQEPFKILKTGKYAKMRGT
HTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54V, V82A L33I, F53L L10I, I13V, K14MV, K20R, M36I, N37D, L63P, I64V, A71V, T91TAS  
>06415A| codons 1-99
PQITLWQRPIVTVVIGGQLREALLDTGADDTIIEEIDLPGRWKPKIVGGIGGLVKVRQYD
QIPVEICGHKVIGTVLVGPTPANIIGRNLLSQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010