Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T215F | N348I | K103N, Y181C | V35K, K104R, K122E, I135V, I142T, E169D, G196R, T200A, H208Y, R211K, K223Q, L228R, A272P, E297K, S322T, I329L, Q334E, R356K, A360T, A376T, E399D |
| >06415A| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNRSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI CQYMDDLYVGSDLEIRQHRAKIEELRQYLLKWGFFTPDKKHQQEPPFRWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPTKDLIAELQKQGEGQWTYQIYQEPFKILKTGKYAKMRGT HTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54V, V82A | L33I, F53L | L10I, I13V, K14MV, K20R, M36I, N37D, L63P, I64V, A71V, T91TAS |
| >06415A| codons 1-99 PQITLWQRPIVTVVIGGQLREALLDTGADDTIIEEIDLPGRWKPKIVGGIGGLVKVRQYD QIPVEICGHKVIGTVLVGPTPANIIGRNLLSQIGCTLNF |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |