Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, L210W, T215Y | D67G, K219N | Y181C, Y188L | V179D | S68G, K103R, D123E, I135T, I202V, E203K, H208Y, R211K, K223E, V245E, A272P, T296S, Y339W, R356RK, M357L, G359S, A371AV, K374KR, K390KR |
| >06400A| codons 1-400 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKGGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIDI CQYMDDLLVGSDLEIGQHRTKVKELRQYLWKWGFYTPDNKHQEEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLSEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTWQIYQEPFKNLKTGKYAKLRSA HTNDVKQLTEVVQRIATESIVIWGKTPKFRLPIQKETWEA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, I84V, L90M | G73C | L10I, I13V, K20V, N37D, D60E, Q61E, I62V, L63P, C67F, A71T, I72T, P79D, T91S, I93L |
| >06400A| codons 1-99 PQITLWQRPIVTVKIGGQLVEALLDTGADDTVLEEMDLPGRWKPKIVGGIGGFVKVRQYE EVPIEIFGHKTTCTVLVGDTPVNVIGRNLMSQLGCTLNF |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |