<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54V, I84V, L90M G73C L10I, I13V, K20V, N37D, D60E, Q61E, I62V, L63P, C67F, A71T, I72T, P79D, T91S, I93L  
>06400A| codons 1-99
PQITLWQRPIVTVKIGGQLVEALLDTGADDTVLEEMDLPGRWKPKIVGGIGGFVKVRQYE
EVPIEIFGHKTTCTVLVGDTPVNVIGRNLMSQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, L210W, T215Y D67G, K219N Y181C, Y188L V179D S68G, K103R, D123E, I135T, I202V, E203K, H208Y, R211K, K223E, V245E, A272P, T296S, Y339W, R356RK, M357L, G359S, A371AV, K374KR, K390KR  
>06400A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKGGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIDI
CQYMDDLLVGSDLEIGQHRTKVKELRQYLWKWGFYTPDNKHQEEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLSEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTWQIYQEPFKNLKTGKYAKLRSA
HTNDVKQLTEVVQRIATESIVIWGKTPKFRLPIQKETWEA

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010