<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, L210W, T215Y K219N K103N, Y181C, G190A   V35M, T39TAEK, K43E, E44A, V106I, V118I, K122E, A158S, T200A, Q207E, H208Y, R211K, K223KQ, A272P, T286A, E297K, G333E, M357MT, A360AT, K366R, T369V, K390R, K395R, E399D  
>06395A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICKELEEAGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSITVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVASDLEIGQHRAKIEELREYLWKWGFYTPDNKHQQEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQEPFKNLKTGKYARTRGT
HTNDVRQLVEAVQKIATESIVIWGKTPKFRLPIQRETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, V82A, L90M L10F, K43T, L89V I13V, K20MR, M36I, L63P, A71V, I93L  
>06395A| codons 1-99
PQITLWQRPFVTVKIGGQLREALLDTGADDTILEEINLPGRWTPKIVGGIGGFIKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNVMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010