<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I47A, L90M V11I, L89V L10I, I13V, K20V, M36I, I62V, L63P, A71I  
>06333A| codons 1-99
PQITLWQRPIITVKIGGQLVEALLDTGADDTILEEINLPGRWKPKMAGGIGGFIKVRQYD
QVPIEICGHKIIGTVLVGPTPVNIIGRNVMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184MIV, L210W, T215Y   L100LI, K103N, Y181YC   P4S, K43E, K101KQ, D123E, I142V, S162Y, V179I, T200IR, R211RK, K223Q, L228R, D250E, A272P, K277R, L283I, I293V, G333E, P345Q, R356K, G359S, A371V, S379C  
>06333A| codons 1-399
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIQKNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIII
CQYVDDLYVGSDLEIGQHRRKIEELRQHLWKWGFYTPDKKHQQEPPFRWMGYELHPDKWT
VQPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQEQFKNLKTGKYAKMRSA
HTNDVKQLTEVVQKIATECIVIWGKTPKFKLPIQKETWE

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010