<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y K219R, N348I     K20R, V35IM, T39A, K43E, E44AD, I94IL, V118I, I135L, S162D, G196E, L205F, H208Y, R211K, H221Y, L228Q, V245M, A272P, I293V, E297K, I329L, G333E, Q334Y, M357S, A376T, T386I, K390R  
>06272A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICAELEEDGKISKIGPENPYNTPV
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGLPHPAGLKKKKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIEQHRTKIEEFRQYLWKWGFYTPDRKYQKEPPFQWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQEYGQWTYQIYQEPFKILKTGKYARSRGA
HTNDVKQLTEAVQKITTESIVIWGKIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M G73T L10I, R41K, K55R, I62IV, L63P, A71V, I72V, P79A  
>06272A| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFVRVRQYD
QVPIEICGHKVVTTVLVGATPVNVIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010