<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, V75M, M184MV, L210W, T215Y K219E Y188L   V35M, T39A, E40F, K43E, V60I, R83K, V106I, V118I, K122E, I135V, E138G, T139M, S162Y, V179VI, H208Y, W212M, D218E, L228H, D237DE, Q242H, I257L, A272P, T286A, I326V, G335S, G359S, S379C  
>06271A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAFLEEEGKISKIGPENPYNTPI
FAIKKKNSDRWRKLMDFRELNKKTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSIPL
DEDFRKYTAFTIPSVNNGMPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIII
YQYVDDLLVGSDLEIGQHRTKIEELRQYLWRMGFYTPEEKHQKEPPFHWMGYELHPEKWT
VHPIVLPEKDSWTVNDLQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQSQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEAVQKIATECIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M L10F, V11I, Q58E, G73S I15V, K20V, M36I, R41K, I62V, L63P, A71V, I72L  
>06271A| codons 1-99
PQITLWQRPFITIKVGGQLVEALLDTGADDTVLEEINLPGKWKPKLIGGIGGFVKVREYD
QVPIEICGHKVLSTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010