<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Y115F, Q151M, M184V V75L, F77L, F116Y, K219E K103N, G190A   E6D, V35I, S68G, A98S, K101Q, K122E, S162D, K166R, T200I, R211K, V245M, A272P, L283I, I293V, E297K, I341L, M357T, K366R, T386I, K390R, I393M  
>06263A| codons 1-399
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLLDLRELNKRTQDFWEVQLGIPHPSGLQKNKSVTVLDVGDAFYSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQDSMTRILEPFRKQNPDIVI
YQYVDDLYVASDLEIGQHRIKIEELRQHLLKWGFTTPDEKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQLYQEPFKNLKTGKYARTRGA
HTNDVRQLTEAVQKIATESIVIWGKIPKFRLPMQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82A L24I L10I, M36I, N37A, I62V, L63P, A71T  
>06263A| codons 1-99
PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEEIALPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010