<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69T_VT, V75M, M184V, L210LW A62V, D67E Y181I   K20KR, I50V, D123E, K166R, D177E, I178M, T200A, R211K, A272P, K277R, E297R, G333E, Q334N, T338S, M357S, A376S, T386I, K390R  
>06260A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKVGPENPYNTPV
FVIKKKESTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEMVI
IQYVDDLYVGSDLEIGQHRAKIEELRQHLWKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQENGQWSYQIYQEPFKNLKTGKYARSRGA
HTNDVKQLTEAVQKISTESIVIWGKIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82A, I84V L10FI, L24I, L33F K20R, E35D, M36MIL, N37DE, L63P, H69Q, A71V, I93L  
>06260A| codons 1-99
PQITLWQRPIVTIKIGGQLREALIDTGADDTVFEDLELPGRWKPKIIGGIGGFIKVRQYD
QIPIEICGQKVIGTVLVGPTPANVIGRNLLTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010