Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L63S, A71V, I72E, V77I, I93L |
| >06236A| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QISIEICGHKVEGTVLIGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | Y188L | V179E | K20R, V35ILPT, K43KE, V60VI, V106VI, L109LI, V118VI, K122E, T200A, Q207E, R211K, V245Q, E248D, A272P, E297A, M357T, V365I, A376S, T377G, T386I, K390R, A400S |
| >06236A| codons 1-400 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTELEEEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVIDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIEI YQYMDDLLVGSDLEIGQHRAKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTRGA HTNDIKQLTEAVQKISGESIVIWGKIPKFRLPIQKETWES |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |