<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82T, I84V L24I L10I, I15V, K20R, E35D, M36I, N37ND, R41K, I62V, L63P, I64V, A71V, Q92QK  
>06137A| codons 1-99
PQITLWQRPIVTIKVGGQLREALIDTGADDTVLEDIDLPGKWKPKIIGGIGGFVKVRQYD
QVPVEICGHKVIGTVVVGPTPTNVIGRNLLTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, L210W, T215Y V75S     V35I, K122E, I135T, I178L, T200I, R211K, K223KQ, V245M, K277R, A288AS, I293V, E297K, V317A, D324E, I326V, R356RK, V365I  
>06137A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEKEGKISKIGPENPYNTPV
FAIKKKNSTKWRKISDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLVI
YQYMDDLYVGSDLEIGQHRIKIEELRQHLWKWGFYTPDKKHQQEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKSLTEVVPLTKEAE
LELAENREILKEPVHGAYYDPSKELVAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRGA
HTNDIKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEA

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010