<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, V75M, M184V, L210W, T215Y K219N K103N V108I, Y318F P4S, E28K, K32E, E40F, K43E, K49R, V118I, K122E, E169D, G196K, Q197E, T200A, E203V, Q207E, H208Y, R211K, V245Q, A272P, V292I, E297K, V317A, S322A, Q334L, K350KR, M357V, R358K, V365I, A371V, T397TI  
>06093A| codons 1-398
PISSIETVPVKLKPGMDGPKVKQWPLTKEKIEALVEICTFLEEEGKISRIGPENPYNTPV
FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI
YQYVDDLYVGSDLEIKEHRAKIVELREYLWKWGFYTPDNKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIIPLTKEAE
LELAENREILKEPVHGAFYDPAKDLIAEIQKQGLGQWTYQIYQEPFKNLRTGKYARVKGA
HTNDIKQLTEVVQKIATESIVIWGKTPKFKLPIQKEIW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82A, L90M F53L L10I, K20R, M36I, N37D, I62V, L63P, H69R, A71I, I72T Q92A
>06093A| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEEIDLPGRWKPKMIVGIGGLVKVRQYD
QVPIEICGRKITGTVLVGPTPANIIGRNLMTAIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010