<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, V75M, L210W, T215Y K70Q, K219N K101E, Y181C, G190S A98G V35L, T39A, E40F, K43Q, K82KR, V118I, K122E, I135T, S162C, Q207E, H208Y, R211K, L228H, V245E, E248V, A272P, K277R, R356K, T369TA, K390R, T397V  
>05973A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICAFLEQEGKISKIGPENPYNTPV
FAIKKKNSDQWRKLMDFRELNRRTQDFWEVQLGIPHPGGLEKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI
CQYMDDLYVSSDLEIGQHRTKIEELREYLWKWGFYTPDNKHQKEPPFHWMGYELHPDKWT
VQPIELPVKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRGA
HTNDVKQLAEAVQKIATESIVIWGKTPKFRLPIQKEVWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M   L10I, T12K, L19I, K20IM, N37D, Q61QH, L63P, A71V, T74S  
>05973A| codons 1-99
PQITLWQRPIVKIKIGGQIMEALLDTGADDTVLEEMDLPGRWKPKLIGGIGGFVKVRQYD
HIPIEICGHKVIGSVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010