<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, Q151M, T215Y A62V, V75I, F77L, N348I Y188L   P4S, T58N, T69N, V106I, R172K, K173N, V189I, T200A, I202V, F214L, L228R, V245K, A272P, T286A, Q334N, G335D, R356K, M357R, K385R, K390R F116W, K223PT
>05971A| codons 1-399
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNNPV
FVIKKKDSNKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYWSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFKNQNPDIVI
YQYMDDLLIGSDLEIGQHRAKVEELRQHLLRWGLYTPDKKHQTEPPFRWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKILKTGKYAKRRGA
HTNDVKQLTEAVQKIATESIVIWGRTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47IV, I54V, I84V, L90M L10F, L33F, Q58E, G73S L19I, D60E, I62V, L63P, C67F, A71V, I72M, V77I, P79A  
>05971A| codons 1-99
PQITLWQRPFVTIKIGGQIKEALLDTGADDTVFEEMNLPGRWKPKIVGGIGGFVKVREYE
QVPIEIFGHKVMSTVLIGATPVNVIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010