<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74LV, L210W, T215Y K219N Y188L   E6D, E44D, K102M, V118I, K122P, D177G, V179VI, H208Y, R211RK, K223E, L228R, T286A, E291D, V292I, K311R, V317A, I329V, G335D, K350R, M357T, T369TA  
>05892A| codons 1-399
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKMKKSVTVLDVGDAYFSIPL
DPDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPGIII
YQYMDDLLVGSDLEIGQHRTKIEELRQYLWKWGFYTPDNKHQEEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIIPLTEEAE
LELAENREILREPVHGAYYDPSKDLIAEVQKQGQDQWTYQIYQEPFKNLRTGKYARTRGA
HTNDVKQLAEAVQKIATESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A, L90M L33F, G73A, L89V L10I, I13V, N37D, R57K, L63P, V77I, I93L  
>05892A| codons 1-99
PQITLWQRPIVTVKIGGQLKEALLDTGADDTVFEEMDLPGRWKPKIIGGIGGFVKVKQYD
QIPIEICGHKAIATVVIGPTPANIIGRNVMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010