<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y181I A98G E6K, K122E, I135L, I142Q, Q197E, R211T, A272P, K366R, T386I, E399D, A400T G359V
>05860A| codons 1-400
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSLNNETPGQRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
IQYMDDLYVGSDLEIGEHRTKIEELRQHLLTWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRVA
HTNDVRQLTEAVQKIATESIVIWGKIPKFKLPIQKETWDT

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   G16E, K20R, M36I, P39S, I62V, L63P, I64V, K70R  
>05860A| codons 1-99
PQITLWQRPLVTIKIEGQLREALLDTGADDTVLEEINLSGRWKPKMIGGIGGFIKVRQYD
QVPVEICGHRAIGTVLVGPTPVNIIGRNLMTQIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010