<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74LV, L210W, T215Y V75VI K101E, G190S   K20R, V35T, E44D, D123E, Q174N, V179I, G196E, R211A, D237DE, A272P, K277R, K281R, L283I, I293V, T296S, E297K, G333E, Q334L, G359S, A371V, K390R  
>05653A| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTELEKDGKISKIGPENPYNTPV
FAIKKKNSTKWRKVIDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKNNPDIII
YQYMDDLYVSSDLEIEQHRTKIEELRQHLWAWGFYTPDKKHQKEPPFLWMGYELHPEKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLIRGTKALTEVVPLSKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQELGQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEVVQKIATESIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A, L90M L10F N37D, L63P, A71V, I93L  
>05653A| codons 1-99
PQITLWQRPFVTIKIGGQLKEALLDTGADDTVLEEMDLPGRWKPKIIGGIGGFVKVRQYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010